Recommendations for Active Biological Evolution

Charles Darwin’s seminal book On the Origin of Species brought one of the greatest revolutions in science. … Fisher, Haldane, Wright and Huxley wrote the Modern Synthesis with genetics. … Waddington, Gould, Pigliucci and Müller brought us the Extended Synthesis. Frank Laukien and others have been extending the synthesis even further, emphasizing how evolution is not just random mutations, but actively accelerated and driven by feedback. … We are in the Age of CRISPR, [with] relevance of evolution to our daily lives, with potent medical implications.
—George Church, Professor of Genetics, Harvard Medical School; Author of Regenesis

Active Biological Evolution is a persuasive argument showing that evolution has been about much more than gradual mutational evolution of genomes … the evidence is incontrovertible.
—Denis Noble, Professor in the Department of Physiology, Anatomy and Genetics, Oxford University; Author of Dance to the Tune of Life

Frank Laukien revolutionizes the way we think about evolution by proposing that feedback on genomic and other molecular changes prior to selection accelerates natural evolution, leading to Active Evolution, which is not just the result of random DNA mutations.
—Avi Loeb, Professor of Science, Harvard University; Author of Extraterrestrial

Synthesizing three waves of evolutionary thinking spanning two centuries, Active Biological Evolution combines powerful writing, compelling arguments, and erudite references to make an electrifying case for feedback-driven, actively accelerated evolution. This book will change how we think about cancer, and it may revolutionize the translational medical applications of evolutionary principles.
—Azra Raza, M.D., Professor of Medicine, Columbia University; Author of The First Cell

Frank Laukien fundamentally challenges the consensus in the Modern Synthesis in evolution. His original and provocative insights are sure to start a wide-ranging discussion.
—Professor Matthias Mann, Director at the Max Planck Institute of Biochemistry

Active Biological Evolution provocatively challenges the scientific community to develop an altered framework on how to interpret biological evolution. Simply put, the insights in this delightful book could impact how the scientific and biomedical world views, and…treats disease.
—Nevan Krogan, Ph.D., Professor of Cellular and Molecular Pharmacology, UCSF

…through his EDITA (Externally Driven, Irreversible & Transferable Adaptation) hypothesis, [Laukien] proposes evolution can occur more rapidly in unicellular life and cancer evolution, and even in multicellular life and in humans.
—Kenneth J. Pienta, M.D., Professor, Johns Hopkins University School of Medicine

Active Biological Evolution is truly remarkable. By re-examining the traditional principles of evolutionary biology from the perspective of modern biology, Frank Laukien proposes wholly new ideas for how species, and even cancer cells, evolve in a non-random manner. This lucid and well-written book will prove to be provocative, controversial, and ultimately prescient…
—Steve Gullans, Ph.D., Co-author, Evolving Ourselves